Industrial Grinder And Mixer For Pharmaceutical Industry
With the rapid development of the biopharmaceutical industry, pharmaceutical companies have increasingly higher requirements for production equipment, especially in the pulverizing and mixing processes, demanding higher standards for equipment efficiency, precision, and reliability. Having cultivated the powder processing field for over 20 years, Baoli Machinery, leveraging its profound understanding of biopharmaceutical industry compliance requirements, core patented technologies, and end-to-end customization capabilities, has built an integrated equipment system covering pulverization, mixing, sieving, and conveying. From grinding active pharmaceutical ingredients (APIs) and mixing biological excipients to the refined processing of traditional Chinese medicine extracts and the pretreatment of aseptic preparation raw materials, Baoli Machinery equipment, with its core advantages of GMP compliance, sterility, precision control, and gentle yet efficient operation, deeply integrates into the entire biopharmaceutical industry chain, providing a solid guarantee for the stability of drug efficacy and production safety, and becoming a core partner for biopharmaceutical companies' large-scale production and innovative R&D.
What We Offer
Baoli Machinery's end-to-end equipment (crushing → conveying → mixing → sieving → granulation), built around "powder" technology, can achieve three core capabilities to the pharmaceutical, biological, and nutrition industries:
Low-temperature & high-cleanliness Pulverization: Achieves controllable pulverization of heat-sensitive or high-value-added materials from 20–800 mesh, reducing the risk of oxidation and degradation;
High-uniformity Mixing: Achieves uniform dispersion of ppm-level trace APIs, vitamins, probiotics, etc., with a CV ≤ 3%, ensuring consistent content;
Sealed and Continuous Operation: All-stainless steel and CIP/SIP design, compatible with isolators, RABS, or sterile rooms, meeting GMP, FDA, and COS certification requirements.
Typical Applications
Active Pharmaceutical
Materials such as antibiotics, hormones, oncology drugs, poorly soluble APIs, and controlled-release microgranules are ultra-finely pulverized to increase their specific surface area, then uniformly mixed in a cone or plow mixer to provide good flowability for direct pressure or dry granulation.
Hebal
Oily medicinal herbs such as fibrous materials, Ganoderma lucidum, Angelica sinensis, and turmeric can be pulverized into 80-200 mesh for traditional Chinese medicine formulas without clogging or heating, preserving the activity of volatile oils.
Biological Product
Vaccines, enzyme preparations, probiotic freeze-dried powders, cell disruption & extraction, low-temperature pulverization and mixing for DNA/RNA and protein extraction, avoiding protein denaturation.
Natural Extract
Phytosterols, lycopene, lutein, green tea, grape seed, and ginseng extracts are ultra-finely pulverized to improve dispersibility; then uniformly adsorbed in a conical screw mixer to produce a water-dispersible powder.
Vitamin
Fat-soluble vitamins A/D/E/K, and compound vitamin premixes, are cryogenically pulverized and then emulsified and encapsulated in a vacuum mixer to improve oxidative stability.
Health Nutrition
Soy protein isolate and whey protein are first ultra-finely pulverized, then uniformly mixed with oligosaccharides, vitamins, and minerals in a mixer. This process is compatible with vacuum feeding and metal detection systems.
Recommended Grinder & Mixer Machine for The Food and Beverage Industry
Why Choose BAOLI Machinery
Baoli Machinery integrates compliance into the entire process of equipment design, production, and inspection. All equipment uses high-quality materials such as 304/316L stainless steel and food-grade seals, with mirror-polished surfaces and no weld seams or dead corners. It passes GMP and FDA certification audits. From raw material procurement to finished product delivery, a multi-stage quality control system is established, equipped with a professional QA/QC team, providing a complete set of documents including material reports, cleaning verification plans, and mechanical test reports, helping customers shorten certification cycles and quickly start production.
Leveraging over 20 years of production experience and a professional technical team, Baoli Machinery offers one-on-one customization services. Based on the customer's material characteristics, production scale, and process requirements, we optimize equipment structure, materials, and parameters. For corrosive materials, we can upgrade to Hastelloy alloy materials; for aseptic production needs, we enhance the sealing and sterilization design; for intelligent production needs, we integrate IoT modules to achieve real-time monitoring and remote control of parameters such as equipment speed, temperature, and current, comprehensively adapting to the personalized needs of different enterprises.
Baoli Machinery has established an after-sales service system covering key global markets. Products enjoy a one-year warranty and lifetime paid warranty, providing dedicated services throughout the process, including equipment installation and commissioning, operator training, and subsequent maintenance and repair, providing solid support for the continuous production of biopharmaceutical companies.